Engineering Mosquitoes’ Genes to Resist Malaria


518 Views

In a basement on the Irvine campus of the University of California, behind a series of five protective doors, two teams of biologists have created a novel breed of mosquito that they hope will help eradicate malaria from the world.
From Our Advertisers

The mosquito has been engineered to carry two ingenious genetic modifications. One is a set of genes that spew out antibodies to the malarial parasite harbored by the mosquito. Mosquitoes with these genes are rendered resistant to the parasite and so cannot spread malaria.

The other modification is a set of genetic elements known as a gene drive that should propel the malaria-resistance genes throughout a natural mosquito population. When a malaria-resistant male mosquito mates with a wild female, the gene drive copies both itself and the resistance genes over from the male chromosome to its female counterpart.

Make a Comment
Make a Comment